MPS Study       Monocenter study Participating Center: Rodiag Radiology Institute   Background Myocardial Perfusion Studies (MPS) are the golden standard for clinical daily cardiology to identify subjects with risk for coronary events. In some cases, however, perfusion may not give a hint to underlying severe coronary artery disease (CAD). As known from Tl-201 tracers, markers of severe and extensive CAD are increased lung-heart-ratio (LHR) and transient ischemic dilation ratio (TID).   Aim This study will examine the prognostic power of clinical variables, exercise data, MPS data, LHR and TID to detect subjects at increased risk for cardiac death and nonfatal myocardial infarction (main outcome variable) as well as risk for CABG, PTCA and hospitalization for heart failure (secondary outcome) in 538 subjects originally imaged from 1994-1996.   Study design Monocenter, observational, retrospective   Inclusion criteria Subjects having undergone physical exercise MPS at out institution between 1994-1996.   Exclusion criteria subjects with MPS and pharmacological stress tests         Ethical Committee accepted   Co-workers 2 MD, 2 Students, my wife, 1 Prof.   Follow-up generation 99% complete at 30. June 2003   Time schedule Close follow-up by June 2003, paper ready for publication by February 2004